FederalOpenFixed dateNational Institutes of Health

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Award ceiling
up to $375,000
Closes
Nov 23, 2026
Last verified
2026-10-22

Awards up to $375,000 per recipient for others (see text field entitled "additional information on eligibility" for clarification), private institutions of higher education, public and state controlled institutions of higher education, closing Nov 23, 2026.

Official pageSign in to trackVerified2026-10-22
Others (see text field entitled "Additional Information on Eligibility" for clarification)Private institutions of higher educationPublic and State controlled institutions of higher educationHealth & Human Services

In one sentence

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) awards up to $375,000 per recipient, open to others (see text field entitled "additional information on eligibility" for clarification), private institutions of higher education, public and state controlled…

Record fields
Program pool (total)
Not confirmed
Total across all awards in this programme. Not an amount any single applicant can receive.
Award ceiling (per project)
$375,000
Award floor
Not confirmed
Typical award
Not confirmed
Deadline
Nov 23, 2026
Deadline type
Fixed date
Opens
Jan 8, 2025
Status
Open
Eligible entities
Others (see text field entitled "Additional Information on Eligibility" for clarification) · Private institutions of higher education · Public and State controlled institutions of higher education
Geography
Not stated
Matching funds
No
Disbursement
Not confirmed
Application effort
Not confirmed
Use of funds
basic and/or mechanistic pain research projects
Currency
USD

How much money is available?

Two different figures govern a programme and they are not interchangeable. The programme pool is what the funder has allocated across every award it will make this cycle. The award ceiling is the most one applicant can be granted.

Program pool (total)Across all awards this cycle
Not stated
Award ceiling (per project)The most one applicant can receive
$375,000

Who can apply?

level
federal
Derived from the source that published this record
entity
Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education, Public and State controlled institutions of higher education
Source field: entity types
industry
Health & Human Services
Source field: industries
demographic
Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs)
Source field: demographics
use
basic and/or mechanistic pain research projects
Source field: use of funds
size limit

Not confirmed

Source field: applicant size limit
clause text

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black…

We store the structured fields above. Clause-by-clause text from the guidelines is not connected for this record.

When does it close?

Nov 23, 202632 daysDeadline type Fixed date
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What can the money be used for?

1 categoryThe source’s own spending categories, and what is not parsed.
basic and/or mechanistic pain research projects

These categories come from the source's own classification. A line-item cost table, where the programme publishes one, lives in the guidelines and is not parsed for this record.

How hard is the application?

1 fieldEffort, match requirement and reimbursement, as the source stated them.
Application effort
Not confirmed
Disbursement
Not confirmed
Matching funds
No

What comparable notices state

291 recordsStated ceilings on open records in the same industry.

Among open records stored under Health & Human Services, 291 of 889 state an award ceiling. Those that do run:

  • 25th percentile$357,500
  • Median$600,000
  • 75th percentile$1,500,000

A statistical estimate, not a prediction. It describes what a set of notices has published in this catalogue on the day you read it, and says nothing about what this programme will award. Records stating no ceiling are excluded rather than counted as zero, and the programme pool — what a funder has across every applicant — is a different column and is never mixed in.

Who has won this programme before?

37928 awardsAwards under the same assistance listing, not under this notice.

37928 federal awards on file under assistance listing 93.121, 93.213, 93.273, 93.846, 93.853, 93.865, 93.866, the programme this notice is published under. These are not awards made under this notice — a listing covers every year the programme runs, and awards under an open notice do not exist yet.

Every award under this programme

Common questions

5 questionsEvery answer is a stored field from this record. Questions the source did not answer are not asked.
How much can one applicant receive?
Up to $375,000 per recipient.
When is the application deadline?
Nov 23, 2026.
Who is eligible to apply?
Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education, Public and State controlled institutions of higher education.
What can the funding be used for?
basic and/or mechanistic pain research projects, as classified by the source.
Is matching funding required?
No. The source states that no matching funds are required.

AI summary of the source text

Optional. Every core field on this record is already above, free and complete.

AI summary of the source text

Studio reads this record’s stored eligibility and materials text and breaks it into separate points, each quoting the exact words it came from. It never writes application prose, never guesses at a field the source did not state, and never estimates anyone’s chances.

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What else is open

Also open from National Institutes of Health
Also open under the same assistance listings

A listing names the programme; a notice names one round of it. These are other rounds open now, not other years of this one.

Provenance
Source pagegrants.gov
Retrieved2026-10-22
MethodAutomated check
First seen2026-09-04
Assistance listings93.121, 93.213, 93.273, 93.846, 93.853, 93.865, 93.866

The official page governs. If the source and this record disagree, the source is correct — programmes change their terms between our checks, so confirm every figure above before you apply.