How much funding is available in total?

$1,000,000 across the whole programme. This is the total the funder has allocated, not an amount any single applicant can receive.

When is the application deadline?

Jun 15, 2028. Response date as stated on grants.gov

Is matching funding required?

No. The source states that no matching funds are required. Cost sharing is false as stated on grants.gov

FederalOpenFixed dateNational Institutes of Health

INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

Award ceiling: up to $200,000
Closes: Jun 15, 2028
Last verified: 2026-09-04

Awards up to $200,000 per recipient for business, city or township governments, county governments, for profit organizations other than small businesses, independent school districts, native american tribal governments (federally recognized), native american tribal organizations (other than federally recognized tribal governments), nonprofit, nonprofits having a 501(c)(3) status with the irs, other than institutions of higher education, nonprofits that do not have a 501(c)(3) status with the irs, other than institutions of higher education, other legal entity, private institutions of higher education, public agency, public and state controlled institutions of higher education, public housing authorities/indian housing authorities, small businesses, special district governments, state governments, tribal government, closing Jun 15, 2028.

Official page Sign in to trackVerified2026-09-04

BusinessCity or township governmentsCounty governmentsFor profit organizations other than small businessesIndependent school districtsNative American tribal governments (Federally recognized)Native American tribal organizations (other than Federally recognized tribal governments)NonprofitNonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationOther Legal EntityPrivate institutions of higher educationPublic AgencyPublic and State controlled institutions of higher educationPublic housing authorities/Indian housing authoritiesSmall businessesSpecial district governmentsState governmentsTribal GovernmentHealth & Human Services

In one sentence

INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed) awards up to $200,000 per recipient, open to business, city or township governments, county governments, for profit organizations other than small businesses, independent school districts,…

Record fields

Program pool (total): $1,000,000
Total across all awards in this programme. Not an amount any single applicant can receive.
Award ceiling (per project): $200,000
Award ceiling is $200,000. Total estimated funding is $1,000,000 with an expected number of 5 awards.
Award floor: Not confirmed
Typical award: Not confirmed
Deadline: Jun 15, 2028
Deadline type: Fixed date
Opens: May 12, 2026
Status: Open
Eligible entities: Business · City or township governments · County governments · For profit organizations other than small businesses · Independent school districts · Native American tribal governments (Federally recognized) · Native American tribal organizations (other than Federally recognized tribal governments) · Nonprofit · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Other Legal Entity · Private institutions of higher education · Public Agency · Public and State controlled institutions of higher education · Public housing authorities/Indian housing authorities · Small businesses · Special district governments · State governments · Tribal Government
Geography: Not stated
Matching funds: No
Disbursement: Not confirmed
Application effort: Not confirmed
Use of funds: Exploratory and developmental research projects that address critical needs for Down syndrome · Assessment of feasibility of novel areas of investigation or new experimental systems · Unique and innovative use of existing methodology to explore new scientific areas · Development of novel techniques, agents, methodologies, models, or applications
Currency: USD

How much money is available?

Two different figures govern a programme and they are not interchangeable. The programme pool is what the funder has allocated across every award it will make this cycle. The award ceiling is the most one applicant can be granted.

Program pool (total)Across all awards this cycle

$1,000,000

Award ceiling (per project)The most one applicant can receive

$200,000

Source wording: “Award ceiling is $200,000. Total estimated funding is $1,000,000 with an expected number of 5 awards.”

Who can apply?

level

federal

Derived from the source that published this record

entity

Business, City or township governments, County governments, For profit organizations other than small businesses, Independent school districts, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofit, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

+9more

, Other Legal Entity, Private institutions of higher education, Public Agency, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Small businesses, Special district governments, State governments, Tribal Government

Source field: entity types

industry

Health & Human Services

Source field: industries

use

Assessment of feasibility of novel areas of investigation or new experimental systems, Development of novel techniques, agents, methodologies, models, or applications, Exploratory and developmental research projects that address critical needs for Down syndrome, Unique and innovative use of existing methodology to explore new scientific areas

Source field: use of funds

size limit

Not stated

Source field: applicant size limit

clause text

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations: Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components are allowed.

We store the structured fields above. Clause-by-clause text from the guidelines is not connected for this record.

When does it close?

Jun 15, 2028646 daysDeadline type Fixed date

Response date as stated on grants.gov

What can the money be used for?

4 categorysThe source’s own spending categories, and what is not parsed.

Exploratory and developmental research projects that address critical needs for Down syndromeAssessment of feasibility of novel areas of investigation or new experimental systemsUnique and innovative use of existing methodology to explore new scientific areasDevelopment of novel techniques, agents, methodologies, models, or applications

These categories come from the source's own classification. A line-item cost table, where the programme publishes one, lives in the guidelines and is not parsed for this record.

How hard is the application?

2 fieldsEffort, match requirement and reimbursement, as the source stated them.

Application effort: Not confirmed
Disbursement: Not confirmed
Matching funds: No
Cost sharing is false as stated on grants.gov

What comparable notices state

333 recordsStated ceilings on open records in the same industry.

Among open records stored under Health & Human Services, 333 of 928 state an award ceiling. Those that do run:

25th percentile$250,000
Median$500,000
75th percentile$1,200,000

A statistical estimate, not a prediction. It describes what a set of notices has published in this catalogue on the day you read it, and says nothing about what this programme will award. Records stating no ceiling are excluded rather than counted as zero, and the programme pool — what a funder has across every applicant — is a different column and is never mixed in.

Who has won this programme before?

22175 awardsAwards under the same assistance listing, not under this notice.

22175 federal awards on file under assistance listing 93.121, 93.173, 93.233, 93.310, 93.351, 93.395, 93.837, 93.838, 93.839, 93.840, 93.846, 93.855, 93.865, 93.866, 93.867, 93.879, the programme this notice is published under. These are not awards made under this notice — a listing covers every year the programme runs, and awards under an open notice do not exist yet.

$1,073,967,938FRED HUTCHINSON CANCER CENTERWA · FY2006
$463,372,200REGENTS OF THE UNIVERSITY OF MICHIGANMI · FY1998
$443,702,768FRED HUTCHINSON CANCER CENTERWA · FY2006
$383,462,829FRED HUTCHINSON CANCER CENTERWA · FY2006
$353,109,533PUBLIC HEALTH INSTITUTECA · FY2014

Every award under this programme

Common questions

6 questionsEvery answer is a stored field from this record. Questions the source did not answer are not asked.

How much can one applicant receive?: Up to $200,000 per recipient. The source states: “Award ceiling is $200,000. Total estimated funding is $1,000,000 with an expected number of 5 awards.”.
How much funding is available in total?: $1,000,000 across the whole programme. This is the total the funder has allocated, not an amount any single applicant can receive.
When is the application deadline?: Jun 15, 2028. Response date as stated on grants.gov
Who is eligible to apply?: Business, City or township governments, County governments, For profit organizations other than small businesses, Independent school districts, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofit, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Other Legal Entity, Private institutions of higher education, Public Agency, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Small businesses, Special district governments, State governments, Tribal Government.
What can the funding be used for?: Exploratory and developmental research projects that address critical needs for Down syndrome, Assessment of feasibility of novel areas of investigation or new experimental systems, Unique and innovative use of existing methodology to explore new scientific areas, Development of novel techniques, agents, methodologies, models, or applications, as classified by the source.
Is matching funding required?: No. The source states that no matching funds are required. Cost sharing is false as stated on grants.gov

AI summary of the source text

Optional. Every core field on this record is already above, free and complete.

AI summary of the source text

Studio reads this record’s stored eligibility and materials text and breaks it into separate points, each quoting the exact words it came from. It never writes application prose, never guesses at a field the source did not state, and never estimates anyone’s chances.

Included with Studio

Provenance

Source pagegrants.gov

Retrieved2026-09-04

MethodAutomated check

First seen2026-09-01

The official page governs. If the source and this record disagree, the source is correct — programmes change their terms between our checks, so confirm every figure above before you apply.