Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Per-recipient award not stated for alaska native and native hawaiian serving institutions, asian american native american pacific islander serving institutions (aanapisiss), business, city or township governments, county governments, eligible agencies of the federal government, faith-based or community-based organizations, for profit organizations other than small businesses, hispanic-serving institutions, historically black colleges and universities (hbcus), independent school districts, indian/native american tribal governments (other than federally recognized), native american tribal governments (federally recognized), native american tribal organizations (other than federally recognized tribal governments), nonprofit, nonprofits having a 501(c)(3) status with the irs, other than institutions of higher education, nonprofits that do not have a 501(c)(3) status with the irs, other than institutions of higher education, other legal entity, private institutions of higher education, public agency, public and state controlled institutions of higher education, public housing authorities/indian housing authorities, regional organizations, small businesses, special district governments, state governments, tribal government, tribally controlled colleges and universities (tccus), u.s. territory or possession, closing Feb 17, 2028.

In one sentence

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed) does not state a per-recipient award amount, open to alaska native and native hawaiian serving institutions, asian american native american pacific islander serving institutions (aanapisiss), business, city…

Record fields
Program pool (total)
Not confirmed
Total across all awards in this programme. Not an amount any single applicant can receive.
Award ceiling (per project)
Not confirmed
No funding amounts stated on source page
Award floor
Not confirmed
Typical award
Not confirmed
Deadline
Feb 17, 2028
Deadline type
fixed
Opens
Jun 17, 2025
Status
Open
Eligible entities
Alaska Native and Native Hawaiian Serving Institutions · Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) · Business · City or township governments · County governments · Eligible Agencies of the Federal Government · Faith-based or Community-based Organizations · For profit organizations other than small businesses · Hispanic-serving Institutions · Historically Black Colleges and Universities (HBCUs) · Independent school districts · Indian/Native American Tribal Governments (Other than Federally Recognized) · Native American tribal governments (Federally recognized) · Native American tribal organizations (other than Federally recognized tribal governments) · Nonprofit · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Other Legal Entity · Private institutions of higher education · Public Agency · Public and State controlled institutions of higher education · Public housing authorities/Indian housing authorities · Regional Organizations · Small businesses · Special district governments · State governments · Tribal Government · Tribally Controlled Colleges and Universities (TCCUs) · U.S. Territory or Possession
Geography
Not stated
Matching funds
No
Disbursement
Not confirmed
Application effort
Not confirmed
Currency
USD

How much money is available?

Two different figures govern a programme and they are not interchangeable. The programme pool is what the funder has allocated across every award it will make this cycle. The award ceiling is the most one applicant can be granted.

Program pool (total)Across all awards this cycle
Not stated
Award ceiling (per project)The most one applicant can receive
Not stated

Source wording: “No funding amounts stated on source page

Who can apply?

industry

Health

Source field: industries
use

Development of methods or agents selective for undruggable target classes, Exploratory and early-stage projects focused on undruggable target classes within intractable human disease

Source field: use of funds
size limit

Not stated

Source field: applicant size limit
clause text

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible. Non-domestic components of U.S. Organizations are not eligible. Foreign components are not allowed.

We store the structured fields above. Clause-by-clause text from the guidelines is not connected for this record.

When does it close?

Feb 17, 2028534 daysfixed deadline

Response date listed as Feb 17, 2028

What can the money be used for?

Exploratory and early-stage projects focused on undruggable target classes within intractable human diseaseDevelopment of methods or agents selective for undruggable target classes

These categories come from the source's own classification. A line-item cost table, where the programme publishes one, lives in the guidelines and is not parsed for this record.

How hard is the application?

Application effort
Not confirmed
Disbursement
Not confirmed
Matching funds
No
Cost sharing is false per labelled field

Who has received this funding?

No award records yet

We hold no prior awards for this programme. That is a gap in what we have connected, not a finding that the programme has never funded anyone — check the official page, which may list past recipients.

Common questions

Every answer below is a stored field from this record. Questions the source did not answer are not asked.

When is the application deadline?
Feb 17, 2028. Response date listed as Feb 17, 2028
Who is eligible to apply?
Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Business, City or township governments, County governments, Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, For profit organizations other than small businesses, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Independent school districts, Indian/Native American Tribal Governments (Other than Federally Recognized), Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofit, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Other Legal Entity, Private institutions of higher education, Public Agency, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Regional Organizations, Small businesses, Special district governments, State governments, Tribal Government, Tribally Controlled Colleges and Universities (TCCUs), U.S. Territory or Possession.
What can the funding be used for?
Exploratory and early-stage projects focused on undruggable target classes within intractable human disease, Development of methods or agents selective for undruggable target classes, as classified by the source.
Is matching funding required?
No. The source states that no matching funds are required. Cost sharing is false per labelled field
Provenance
Source pagegrants.gov
Retrieved2026-09-01
MethodAutomated check
First seen2026-09-01

The official page governs. If the source and this record disagree, the source is correct — programmes change their terms between our checks, so confirm every figure above before you apply.