NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

Per-recipient award not stated for alaska native and native hawaiian serving institutions, asian american native american pacific islander serving institutions (aanapisiss), business, city or township governments, county governments, eligible agencies of the federal government, faith-based or community-based organizations, for profit organizations other than small businesses, hispanic-serving institutions, historically black colleges and universities (hbcus), independent school districts, indian/native american tribal governments (other than federally recognized), native american tribal governments (federally recognized), native american tribal organizations (other than federally recognized tribal governments), non-domestic (non-u.s.) entities (foreign organizations), nonprofit, nonprofits having a 501(c)(3) status with the irs, other than institutions of higher education, nonprofits that do not have a 501(c)(3) status with the irs, other than institutions of higher education, other legal entity, private institutions of higher education, public agency, public and state controlled institutions of higher education, public housing authorities/indian housing authorities, regional organizations, small businesses, special district governments, state governments, tribal government, tribally controlled colleges and universities (tccus), u.s. territory or possession, closing Jan 7, 2028.

In one sentence

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed) does not state a per-recipient award amount, open to alaska native and native hawaiian serving institutions, asian american native american pacific islander serving institutions (aanapisiss), business,…

Record fields
Program pool (total)
Not confirmed
Total across all awards in this programme. Not an amount any single applicant can receive.
Award ceiling (per project)
Not confirmed
Opportunity PA-25-304 references a PARENT funding opportunity; the actual funding amounts, per-award caps, and total pool are defined in the parent R21 Notice of Funding Opportunity (NOFO). These amounts are not stated on this page.
Award floor
Not confirmed
Typical award
Not confirmed
Deadline
Jan 7, 2028
Deadline type
unknown
Opens
Dec 18, 2024
Status
Open
Eligible entities
Alaska Native and Native Hawaiian Serving Institutions · Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) · Business · City or township governments · County governments · Eligible Agencies of the Federal Government · Faith-based or Community-based Organizations · For profit organizations other than small businesses · Hispanic-serving Institutions · Historically Black Colleges and Universities (HBCUs) · Independent school districts · Indian/Native American Tribal Governments (Other than Federally Recognized) · Native American tribal governments (Federally recognized) · Native American tribal organizations (other than Federally recognized tribal governments) · Non-domestic (non-U.S.) Entities (Foreign Organizations) · Nonprofit · Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education · Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education · Other Legal Entity · Private institutions of higher education · Public Agency · Public and State controlled institutions of higher education · Public housing authorities/Indian housing authorities · Regional Organizations · Small businesses · Special district governments · State governments · Tribal Government · Tribally Controlled Colleges and Universities (TCCUs) · U.S. Territory or Possession
Geography
Not stated
Matching funds
No
Disbursement
Not confirmed
Application effort
Not confirmed
Currency
USD

How much money is available?

Two different figures govern a programme and they are not interchangeable. The programme pool is what the funder has allocated across every award it will make this cycle. The award ceiling is the most one applicant can be granted.

Program pool (total)Across all awards this cycle
Not stated
Award ceiling (per project)The most one applicant can receive
Not stated

Source wording: “Opportunity PA-25-304 references a PARENT funding opportunity; the actual funding amounts, per-award caps, and total pool are defined in the parent R21 Notice of Funding Opportunity (NOFO). These amounts are not stated on this page.

Who can apply?

use

Behavioral research, Biomedical research, Clinical research, Early and conceptual stage research, Exploratory and developmental research projects, New agents, New applications, New methodologies, New models, Novel techniques

Source field: use of funds
size limit

Not stated

Source field: applicant size limit
clause text

This is a parent funding opportunity for the NIH Exploratory/Developmental (R21) grant mechanism. Applicants should consult the full parent Notice of Funding Opportunity (NOFO) for complete eligibility requirements, including any institutional requirements, project-specific restrictions (e.g., "Clinical Trial Not Allowed"), and additional eligibility criteria.

We store the structured fields above. Clause-by-clause text from the guidelines is not connected for this record.

When does it close?

Jan 7, 2028493 daysunknown deadline

This is labeled as "Response date" on the grants.gov page. NIH R21 grants typically operate on rolling deadlines; this date likely represents a specific submission deadline for this cycle.

What can the money be used for?

Exploratory and developmental research projectsEarly and conceptual stage researchNovel techniquesNew agentsNew methodologiesNew modelsNew applicationsBiomedical researchBehavioral researchClinical research

These categories come from the source's own classification. A line-item cost table, where the programme publishes one, lives in the guidelines and is not parsed for this record.

How hard is the application?

Application effort
Not confirmed
Disbursement
Not confirmed
Matching funds
No
Cost sharing is listed as false on the grants.gov page.

Who has received this funding?

No award records yet

We hold no prior awards for this programme. That is a gap in what we have connected, not a finding that the programme has never funded anyone — check the official page, which may list past recipients.

Common questions

Every answer below is a stored field from this record. Questions the source did not answer are not asked.

When is the application deadline?
Jan 7, 2028. This is labeled as "Response date" on the grants.gov page. NIH R21 grants typically operate on rolling deadlines; this date likely represents a specific submission deadline for this cycle.
Who is eligible to apply?
Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Business, City or township governments, County governments, Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, For profit organizations other than small businesses, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Independent school districts, Indian/Native American Tribal Governments (Other than Federally Recognized), Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Non-domestic (non-U.S.) Entities (Foreign Organizations), Nonprofit, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Other Legal Entity, Private institutions of higher education, Public Agency, Public and State controlled institutions of higher education, Public housing authorities/Indian housing authorities, Regional Organizations, Small businesses, Special district governments, State governments, Tribal Government, Tribally Controlled Colleges and Universities (TCCUs), U.S. Territory or Possession.
What can the funding be used for?
Exploratory and developmental research projects, Early and conceptual stage research, Novel techniques, New agents, New methodologies, New models, New applications, Biomedical research, Behavioral research, Clinical research, as classified by the source.
Is matching funding required?
No. The source states that no matching funds are required. Cost sharing is listed as false on the grants.gov page.
Provenance
Source pagegrants.gov
Retrieved2026-09-01
MethodAutomated check
First seen2026-09-01

The official page governs. If the source and this record disagree, the source is correct — programmes change their terms between our checks, so confirm every figure above before you apply.